孙杨 主治医师/讲师 学科(方向):胶质瘤侵袭及分化的相关研究 所在系部:附属翔安医院神经外科 办公电话:0592-218XXXX 邮 箱:sunyang198568@163.com |

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研究领域(200~300字介绍):
主要是研究领域是人的大脑恶性胶质瘤的的侵袭及分化等相关变化的内在机制。目前在演课题UCA1/ miR-122通过调节FGF1能够增强胶质瘤侵袭的机理,以及其病理生理学的相关变化,以及环装RNA在胶质瘤侵袭分化中起到的作用。
学习经历(高等教育经历<本、硕、博>均需完整)
2004~2009第四军医大学临床医学专业医学学士;
2009~2012第四军医大学内科学专业 医学硕士;
工作经历(需完整、连续,本校职称晋升过程要完整,博士后经历也需填写)
2012~2018第四军医大学唐都医院 主治医师/讲师;
2018~至今厦门大学附属翔安医院 主治医师/讲师;
代表性成果(自己选择,不限篇数):
(1)Lei Wanga,b,c,*,Yang Sun c,*, Xinmin Xud, Xiuzhen Dongb and Feng Gaoa Real-time imaging of epileptic seizures in rats using electrical impedance tomographyNeuroReport 2017 Aug 2;28(11):689-693
(2)Yang Sun,*1Jun-Gong Jin,*1 Wei-Yang Mi,† Hao-Wu,* Shi-Rong Zhang,‡ Qiang Meng,* and Shi-Tao Zhang‡, Long Noncoding RNA UCA1 Targets miR-122 to Promote Proliferation Migration, and Invasion of Glioma Cells, Oncology Research, 2018 Jan 19;26(1):103-110
(3) Haitao Zhang, Guodong Gao, Yu Zhang,Yang Sun, Huanfa Li, Shan Dong, Wei Ma, Bei Liu,Weiwen Wang, Hao Wu & Hua Zhang Glucose Deficincy Elevates AcidSensing Ion Channel 2a Expression and Increases Seizure Susceptibility in Temporal Lobe Epilepsy Scientific RepoRts 2017 Jul 19;7(1):5870
(4)He F1, Liu B2, Meng Q2, Sun Y2, Wang W2, WangC3 Modulation ofmiR-146a/complement factor H-mediated inflammatory responses in a rat model of temporal lobe epilepsyBiosci Rep. 2016 Dec 23;36(6)
(5)Yang J1, He F, Meng Q, Sun Y, Wang W, Wang CInhibiting HIF-1α Decrease xpression of TNF-α and Caspase-3 in Specifc Brain Regions Exposed Kainic Acid–Induced Status EpilepticusCell Physiol Biochem. 2016;38(1):75-82.
(6)Sun Y,Yang JX,Liu B,Yang BY,Meng Q. Long non-coding RNA homeobox (HOX) A11-AS promotes malignant progression of glioma by targeting miR-124-3p[J]Neoplasma.2018;65(4):505-514(5-Year IF:1.69)
(7)Yang JX,Sun Y,Gao L,Meng Q,Yang BY. Long non-coding RNA DANCR facilitates glioma malignancy by sponging miR-33a-5p[J]Neoplasma.2018 Sep 19;65(5):790-798(5-Year IF:1.69)
(8)Meng Q,Yang BY,Liu B,Yang JX,Sun Y. Long non-coding RNA SNHG6 promotes glioma tumorigenesis by sponging miR-101-3p[J]Int J Biol Markers.2018 May;33(2):148-155.(5-Year IF:1.49)
(9)Yang BY,Meng Q,Sun Y,Gao L,Yang JX.Long non-coding RNA SNHG16 contributes to glioma malignancy by competitively binding miR-20a-5p with E2F1J Biol Regul Homeost Agents.2018 Mar-Apr;32(2):251-261.(5-Year IF: 1.39)
主持过的重要课题:
1国家自然科学基金青年项目,81601123,星形胶质细胞Bestrophin通过调节紧张性抑制在癫痫发作终止中的作,2017/01-2020/12,30万元,未结题,参与人
已申请的专利:
1.孙杨,脑外科手术定位器, 2017.09.25,中国, ZL201721232107.4