周军

2018年12月11日 11:32  点击:[]

周军硕导/主任药师

学科(方向):临床药理学

所在系部:附属翔安医院药学部

办公电话:0592-218XXXX

邮 箱:junzhou@xah.xmu.edu.cn

研究领域

主要研究领域为临床疾病个体化诊疗研究;新型药物输送系统研究;中药药理学

学习经历

1991~1995新疆医科大学药学专业理学学士;

2003~2006第四军医大学药理学专业 医学硕士;

2006~2009第四军医大学药理学专业 医学博士;

工作经历

2017~ 厦门大学附属翔安医院药学部主任药师

1995~2017历任新疆军区总医院药师;主管药师副主任药师 主任药师副教授

代表性成果

1.Jun Zhou, Xiao Li Sun, Wang S Wang. Micelle-mediated extraction and cloud-point preconcentration of osthole and imperatorin from Cnidium monnieri with analysis by high performance liquid chromatography. Journal of Chromatography A, 2008, 1200, 93–99.

2.Jun Zhou, Wang S Wang, Xiao Li Sun. Determination of osthole in rat plasma by high performance liquid chromatograph using cloud-point extraction. Analytica chimica acta 2008, 608, 158–164.

3. Wen-Bo Liu*,Jun Zhou*, Jiang Bing Sun, Yan Qu, Xia Li, Guang-Xia Ma, Ke-Liang Xie, Xiao-Li Sun, Zhou Fei. Neuroprotective effect of osthole on MPP+-induced cytotoxicity in PC12 cells via inhibition of mitochondrial dysfunction and ROS production. Neurochemistry international 2010, 57, 206-215. (共同第一作者)

4. Xiao-dong Chao*,Jun Zhou*, Jiang Bing Sun, Wenbo Liu, Wenpeng Dong, Yan Qu, Xiaofan Jiang, Xituan Ji, Haining Zhen, Zhou Fei. Neuroprotective effect of osthole against acute ischemic stroke on middle cerebral ischemia occlusion in rats. Brain research 2010. 1363, 206-211. (共同第一作者)

5.Jun Zhou, Ping Zeng, Hong Hai Tu, Feng Qiao Wang. Development and application of high–performance liquid chromatography for the study of ampelopsin pharmacokinetics in rat plasma using cloud-point extraction. Journal of Separation Science. 2011. 34. 160-168.

6.Jun Zhou, Jiang Bing Sun, Ping Zeng, Zhao Hui Cheng, Jing Liu, Feng Qiao Wang, Ruo Jun Qian. Application of hollow fiber liquid phase microextraction coupled with high-performance liquid chromatography for the study of the osthole pharmacokinetics in cerebral ischemia hypoperfusion rat plasma. Journal of Chromatography B. 2011.879. 2304–2310.

7.Jun Zhou, Jiang Bing Sun, Jing Liu, Zhao Hui Cheng, Ping Zeng, Feng Qiao Wang. Orthogonal array design for the optimization of hollow fiber based liquid phase microextraction combined with high performance liquid chromatography for the study of the magnoflorine pharmacokinetics in rat plasma. Analytical and Bioanalytical Chemistry. 2012.403.1951-1960.

8.Jun Zhou, Ping Zeng, Jiang Bing Sun, Feng Qiao Wang, Qiong Zhang. Application of Two-phase hollow fiber liquid phase microextraction coupled with high–performance liquid chromatography for the study of the echinacoside pharmacokinetics in Parkinson's disease rat plasma. Journal of Pharmaceutical and Biomedical Analysis. 2013. 81-82, 27-33.

9.Jun Zhou, Qiong Zhang, Jiang Bing Sun, Feng Qiao Wang Ping Zeng. Simultaneous separation and determination of four phenylethanoid glycosides in plasma sample after oral administration of Cistanche salsa extract by microemulsion liquid chromatography. Journal of Chromatography B. 2014. 951-952, 24-31. IF=2.97 SCI

10.Jun Zhou, Qiong Zhang, Jiang Bing Sun, Xiao Li Sun, Ping Zeng. Two-phase hollow fiber liquid phase microextraction based on magnetofluid for simultaneous determination of Echinacoside, Tubuloside B, Acteoside and Isoacteoside in rat plasma after oral administration of Cistanche salsa extract by high performance liquid chromatography. Journal of Pharmaceutical and Biomedical Analysis. 2014. 94, 30-35.

11.Rui Juan Song, Feng Ping Pu,Jun Zhou*, Jiang Bing Sun, Ping Zeng, Qiong Zhang. Three-phase hollow fiber liquid-phase microextraction based on a magnetofluid for the analysis of aristolochic acids in plasma by high performance liquid chromatography. Journal of Separation Science. 2014. 37(13):1622-31. (通讯作者)

12.Jun Zhou, Jiang Bing Sun, Xin Yu Xu, Zhao Hui Cheng, Ping Zeng, Feng Qiao Wang, Qiong Zhang. Application of mixed cloud point extraction for the analysis of six flavonoids in Apocynum venetum leaf samples by high performance liquid chromatography Journal of Pharmaceutical and Biomedical Analysis. 2015. 107, 273-279.

13. Rui Juan Song, Feng Ping Pu,Jun Zhou*. Microemulsion liquid chromatographic method for simultaneous separation and determination of six flavonoids in plasma sample after oral administration of Apocynum venetum leaf extract Journal of Chromatography B. 2015. 995, 8-14. (通讯作者)

14.Jun Zhou, Jiang Bing Sun, Qiao Feng Wang. Determination of isoquercitrin in rat plasma by high performance liquid chromatography coupled with a novel synergistic cloud point extraction. Journal of Chromatography B. 2017. 1072. 136 -142

15. Jia Xin Chen, Jiang Bing Sun,Jun Zhou*. Application of hollow-fiber liquid microextraction couple with surfactant ion pair solvent for the study of the acrylamide and glycidamide in high temperature processed medicinal plant materials. New Journal of Chemistry Article Online (通讯作者)

主持过的重要课题

1. “脑缺血病理状态下大花罗布麻叶主要黄酮类成分体内药动学过程及其对相关神经递质影响的研究”新疆维吾尔自治区自然科学基金面上项目

2. “管花肉苁蓉中松果菊苷对MPTP诱导C57BL小鼠帕金森病和MPP+诱导PC12细胞损伤的保护作用研究”全军医药卫生科研基金课题

已申请的专利

1. “一种中药蛇床子中总香豆素的提取方法”国家发明专利授权专利号201210462636.9

    2. “同时测定大花罗布麻叶中6种黄酮类成分含量的HPLC方法”国家发明专利授权专利号201410510844.0

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